Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621517 | 0.87 | MEN1 (0.38) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL620869 | 0.83 | GABRP (0.41) | HTR1ADRD2DRD4KCNH2KDM4E | |
| SCHEMBL619988 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP2D6HTR1ADRD2DRD4 | |
| SCHEMBL621518 | 0.80 | HTR1A (0.35) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL618802 | 0.79 | MEN1 (0.39) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL18081996 | 0.79 | HAVCR2 (0.34) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL6015536 | 0.79 | KCNH2 (0.39) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL618124 | 0.79 | CYP1A2 (0.40) | CYP1A2CYP2D6SSTR4HTR1ADRD2 | |
| SCHEMBL618272 | 0.78 | GABRP (0.39) | CYP1A2CYP2D6CYP3A4CYP2C9KDM4E | |
| SCHEMBL21281480 | 0.78 | HTR1A (0.33) | CYP1A2CYP2D6SSTR4HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742026-B1 | SWEET FLAVOR MODIFIER | SENOMYX INC (US) | 2016-10-05 | — | — | EP | claimed |