Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 9/20 | 0.37 |
| ▸ | DHFR | P00374 | 5/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621168 | 0.82 | KCNA5 (0.38) | KCNH2HTR1ADRD2DRD4SSTR4 | |
| SCHEMBL621517 | 0.80 | MEN1 (0.38) | KCNH2DCPSCYP1A2CYP2D6HTR1A | |
| SCHEMBL618124 | 0.79 | CYP1A2 (0.40) | KCNH2CYP1A2CYP2D6HTR1ADRD2 | |
| SCHEMBL621518 | 0.79 | HTR1A (0.35) | KCNH2CYP1A2CYP2D6HTR1ADRD2 | |
| SCHEMBL21281480 | 0.79 | HTR1A (0.33) | KCNH2CYP1A2CYP2D6HTR1ADRD2 | |
| SCHEMBL620869 | 0.79 | GABRP (0.41) | KCNH2HTR1ADRD2DRD4KDM4E | |
| SCHEMBL18106918 | 0.79 | CYP1A2 (0.36) | KCNH2DCPSCYP1A2CYP2D6HTR1A | |
| SCHEMBL18081996 | 0.78 | HAVCR2 (0.34) | KCNH2CYP1A2CYP2D6HTR1ADRD2 | |
| SCHEMBL6015553 | 0.78 | DCPS (0.43) | KCNH2DCPSDHFRCSNK1A1CSNK1D | |
| SCHEMBL6015550 | 0.76 | KDM4E (0.53) | DCPSDHFRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |