Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618124 | 0.86 | CYP1A2 (0.40) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL621518 | 0.86 | HTR1A (0.35) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL621517 | 0.79 | MEN1 (0.38) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL6015536 | 0.79 | KCNH2 (0.39) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL18106918 | 0.78 | CYP1A2 (0.36) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL620869 | 0.78 | GABRP (0.41) | HTR1ADRD2DRD4KCNH2NPC1 | |
| SCHEMBL17057292 | 0.77 | CYP1A2 (0.34) | NPC1RAB9ACYP1A2CYP2D6KDM4E | |
| SCHEMBL18081996 | 0.77 | HAVCR2 (0.34) | HTR1ADRD2DRD4KCNH2SSTR4 | |
| SCHEMBL619988 | 0.74 | CYP1A2 (0.41) | HTR1ADRD2DRD4KCNH2CYP1A2 | |
| SCHEMBL618272 | 0.73 | GABRP (0.39) | RAB9ACYP1A2CYP2D6KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |