SCHEMBL1810892

SCHEMBL1810892

CO[Si](CCCNC(=O)O)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
TSHR P16473 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ADRA1A P35348 1/20 0.32
ACHE P22303 1/20 0.32
POLB P06746 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3865298 0.94 EPHX1 (0.39) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL4637404 0.87 EPHX1 (0.35) EPHX1TSHRMEN1KMT2AALDH1A1
SCHEMBL20954114 0.86 CYP2D6 (0.36) EPHX1TSHRMEN1KMT2ACYP2D6
SCHEMBL254189 0.84 EPHX1 (0.46) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL6948794 0.84 EPHX1 (0.32) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL18180992 0.83 TSHR (0.44) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL467687 0.83 EPHX1 (0.55) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL960689 0.83 KDM4E (0.56) TSHRKDM4EMAPK1HIF1AALDH1A1
SCHEMBL10016193 0.81 NPC1 (0.37) EPHX1TSHRKDM4EMAPK1HIF1A
SCHEMBL22174072 0.81 TSHR (0.52) TSHRKDM4EMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747306-A1 THERMALLY CONDUCTIVE TWO-COMPONENT COMPOSITION WITH CURING RETARDER Sika Technology AG (CH) 2026-05-27 EP claimed
WO-2025017022-A1 THERMALLY CONDUCTIVE TWO-COMPONENT COMPOSITION WITH CURING RETARDER SIKA TECHNOLOGY AG (CH) 2025-01-23 WO claimed
EP-4495175-A1 THERMALLY CONDUCTIVE TWO-COMPONENT COMPOSITION WITH CURING RETARDER Sika Technology AG (CH) 2025-01-22 EP claimed
CN-115626840-A Concrete durability protection material for sewage treatment plant and application thereof 重庆锦弘新材料技术工程有限公司 2023-01-20 CN claimed
US-20230002537-A1 Organic-inorganic hybrid material, fabrication process of the same and its starting material CHANDA CHEMICAL CORP. (TW) 2023-01-05 US claimed
EP-3972945-A1 FLEXIBLE MORTAR COMPOSITIONS Sika Technology AG (CH) 2022-03-30 EP claimed
US-20210070914-A1 Organic-inorganic hybrid material, fabrication process of the same and its starting material CHANDA CHEMICAL CORP. (TW) 2021-03-11 US claimed
CN-111468044-A Internal coil heating reactor and method for producing 3-isocyanatopropyl trimethoxy silane by using same 江西宏柏新材料股份有限公司 2020-07-31 CN claimed
EP-3256535-B1 ELASTOMERIC SILICONE EMULSION FOR COATING APPLICATIONS WACKER CHEMIE AG (DE) 2018-06-20 EP claimed
EP-3256535-A1 ELASTOMERIC SILICONE EMULSION FOR COATING APPLICATIONS Wacker Chemie AG (DE) 2017-12-20 EP claimed
WO-2016128333-A1 ELASTOMERIC SILICONE EMULSION FOR COATING APPLICATIONS WACKER CHEMIE AG (DE) 2016-08-18 WO claimed
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
US-20080248289-A1 Zinc Oxide Nanoparticles MERCK PATENT GESELLSCHAFT (DE) 2008-10-09 US claimed
EP-0476564-B1 Latent carbamate silicon coupling agents and process for preparation and use OSI SPECIALTIES INC (US) 1995-12-27 EP claimed
EP-0476564-A1 Latent carbamate silicon coupling agents and process for preparation and use OSi Specialties, Inc. (US) 1992-03-25 EP claimed
EP-4739727-A1 CURING AGENT COMPOSITION COMPRISING SALTS OF THIOCYANATE Hilti Aktiengesellschaft (LI) 2026-05-13 EP disclosed
US-5220047-A CARBAMATE SILICON COMPOUNDS AS LATENT COUPLING AGENTS AND PROCESS FOR PREPARATION AND USE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-15 US disclosed
EP-0476564-A1 Latent carbamate silicon coupling agents and process for preparation and use OSi Specialties, Inc. (US) 1992-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002537-A1 Organic-inorganic hybrid material, fabrication process of the same and its starting material INTS9, CA4, OR10J3 EPHX1 3356/4885TSHR 4885/4885KDM4E 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.