SCHEMBL4637404

SCHEMBL4637404

CCO[Si](CCCNC(=O)O)(OC)OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.35
EGLN1 Q9GZT9 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 3/20 0.32
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2145050 0.91 EGLN1 (0.37) EPHX1EGLN1CA12CA1CA2
SCHEMBL27904658 0.89 EGLN1 (0.36) EPHX1EGLN1CA12CA1CA2
SCHEMBL1810892 0.87 EPHX1 (0.36) EPHX1MEN1KMT2AACHETSHR
SCHEMBL16248012 0.86 ACHE (0.44) EPHX1KMT2AACHEHDAC3HDAC4
SCHEMBL3477710 0.86 EPHX1 (0.52) EPHX1CA12CA1CA2CA9
SCHEMBL3860224 0.85 CA12 (0.39) EPHX1EGLN1CA12CA1CA2
SCHEMBL728060 0.84 EPHX1 (0.34) EPHX1CA12CA1CA2CA9
SCHEMBL940903 0.83 PAOX (0.38) EPHX1EGLN1CA12CA1CA2
SCHEMBL6537039 0.82 EPHX1 (0.52) EPHX1CA12CA1CA2CA9
SCHEMBL4355837 0.82 EPHX1 (0.42) EPHX1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed