Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598647 | 0.84 | NQO2 (0.62) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| SCHEMBL317958 | 0.82 | NQO2 (0.58) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| SCHEMBL19971558 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EGAAATM | |
| SCHEMBL94267 | 0.79 | ALDH1A1 (0.70) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| SCHEMBL11264113 | 0.78 | NQO2 (0.40) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| SCHEMBL29361191 | 0.75 | KDM4E (0.60) | ALDH1A1KMT2AKDM4EMAPK1BLM | |
| SCHEMBL26806952 | 0.75 | KDM4E (0.60) | ALDH1A1KMT2AKDM4EMAPK1BLM | |
| SCHEMBL31598603 | 0.74 | ALDH1A1 (0.50) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| SCHEMBL28567770 | 0.74 | NQO2 (0.61) | ALDH1A1NQO2KMT2AKDM4EGAA | |
| Maleic Acid SCHEMBL123790 | 0.74 | ALDH1A1 (0.63) | ALDH1A1NQO2KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3273802-A1 | USE OF A TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE | Erber Aktiengesellschaft (AT) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016154640-A1 | USE OF A TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE | ERBER AKTIENGESELLSCHAFT (AT) | 2016-10-06 | — | — | WO | disclosed |