SCHEMBL19971558

SCHEMBL19971558

CC(=O)c1cccc2nc3c(C(=O)O)cccc3nc12

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
KDM4E B2RXH2 4/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 1/20 0.41
ALOX15 P16050 2/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
DHODH Q02127 3/20 0.41
ACHE P22303 1/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30548734 0.90 ALDH1A1 (0.88) ALDH1A1KDM4EGAAKMT2AATM
SCHEMBL68995 0.90 ALDH1A1 (0.88) ALDH1A1KDM4EGAAKMT2AATM
SCHEMBL94267 0.87 ALDH1A1 (0.70) ALDH1A1KDM4EGAAKMT2AATM
Phenazine-1-Carboxylic Acid SCHEMBL27752237 0.85 ALDH1A1 (0.93) ALDH1A1KDM4EGAAKMT2AATM
Phenazine-1-Carboxylic Acid SCHEMBL27884214 0.85 ALDH1A1 (1.00) ALDH1A1KDM4EGAAKMT2ACYP1A2
Phenazine-1-Carboxylic Acid SCHEMBL122864 0.85 ALDH1A1 (1.00) ALDH1A1KDM4EGAAKMT2ACYP1A2
Phenazine-1-Carboxylic Acid SCHEMBL28160016 0.85 ALDH1A1 (1.00) ALDH1A1KDM4EGAAKMT2ACYP1A2
Phenazine-1-Carboxylic Acid SCHEMBL29370801 0.85 ALDH1A1 (1.00) ALDH1A1KDM4EGAAKMT2ACYP1A2
SCHEMBL5448034 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EGAAKMT2AATM
Phenazine-1-Carboxylic Acid SCHEMBL28714733 0.83 ALDH1A1 (0.96) ALDH1A1KDM4EGAAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4022047-B1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL DSM Austria GmbH (AT) 2026-04-22 EP disclosed
EP-3273802-B1 USE OF A TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE DSM Austria GmbH (AT) 2025-06-25 EP disclosed
CN-120058622-A Phenazine statin compound, and preparation method and application thereof 深圳技术大学 2025-05-30 CN disclosed
CN-112442489-B Improved polypeptides for converting substrate 3-keto-deoxynivalenol to 3-epi-deoxynivalenol 爱尔伯股份公司 2025-02-25 CN disclosed
US-20230235297-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI-DEOXYNIVALENOL DSM Austria GmbH (AT) 2023-07-27 US disclosed
EP-4162031-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI-DEOXYNIVALENOL DSM Austria GmbH (AT) 2023-04-12 EP disclosed
US-20220372450-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL DSM Austria GmbH (AT) 2022-11-24 US disclosed
EP-4022047-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL Erber Aktiengesellschaft (AT) 2022-07-06 EP disclosed
CN-113832119-A Improved polypeptide capable of converting substrate 3-ketodeoxynivalenol into 3-epi-deoxynivalenol 艾尔柏股份公司 2021-12-24 CN disclosed
WO-2021249980-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI-DEOXYNIVALENOL ERBER AKTIENGESELLSCHAFT (AT) 2021-12-16 WO disclosed
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ERBER AKTIENGESELLSCHAFT (AT) 2021-05-11 US disclosed
CN-112442489-A Improved polypeptide for converting substrate 3-keto-deoxynivalenol into 3-epi-deoxynivalenol 爱尔伯股份公司 2021-03-05 CN disclosed
WO-2021038026-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL ERBER AKTIENGESELLSCHAFT (AT) 2021-03-04 WO disclosed
US-20180080011-A1 TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE ERBER AKTIENGESELLSCHAFT (AT) 2018-03-22 US disclosed
CN-107109375-A The purposes of the alcohol dehydrogenase of trichothecene is converted, for converting the method for trichothecene compounds and the additive of conversion trichothecene 爱尔伯股份公司 2017-08-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372450-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL VIP, PREP, NGLY1 ALDH1A1 4220/4885KDM4E 2065/4885GAA 980/4885
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ADH5, IDH3A, ADH4 ALDH1A1 268/4885KDM4E 2762/4885GAA 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.