Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317958 | 0.84 | NQO2 (0.58) | NQO2LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL18113724 | 0.78 | ALDH1A1 (0.49) | NQO2LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL7760052 | 0.75 | RAB9A (0.57) | NQO2LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL3961416 | 0.74 | LMNA (0.46) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL10555620 | 0.73 | ALDH1A1 (0.70) | LMNAALDH1A1ACHEMAPTRAB9A | |
| SCHEMBL7534418 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ACHEMAPTRAB9ANPC1 | |
| SCHEMBL9409728 | 0.72 | PARP1 (0.48) | HDAC6ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6213177 | 0.71 | NQO2 (0.59) | NQO2LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL8013103 | 0.71 | CA12 (0.41) | LMNAALDH1A1MAPTPOLBPKM | |
| SCHEMBL3415803 | 0.70 | LMNA (0.71) | LMNAMETAP2METAP1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050790-A1 | Preparation of alpha-chlorinated nitrogen heterocycles | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |