Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396698 | 0.94 | ECE1 (0.42) | FAAHCNR1CNR2PLA2G2AECE1 | |
| SCHEMBL18753010 | 0.90 | PTPN1 (0.41) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL18753016 | 0.88 | PTPN1 (0.39) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL20113878 | 0.83 | FAAH (0.51) | FAAHCNR1CNR2EPHX2TSHR | |
| SCHEMBL14894607 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL2011728 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL2011072 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL2010277 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL2011462 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL398562 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3348548-A1 | NITRIC OXIDE-RELEASING PRODRUG MOLECULE | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2018-07-18 | — | — | EP | claimed |
| US-10280138-B2 | Nitric oxide donating derivatives of fluprostenol | NICOX S.A. (FR) | 2019-05-07 | — | — | US | disclosed |
| EP-3348548-A1 | NITRIC OXIDE-RELEASING PRODRUG MOLECULE | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2018-07-18 | — | — | EP | disclosed |
| US-20180118677-A1 | NITRIC OXIDE DONATING DERIVATIVES OF FLUPROSTENOL | NICOX S.A. (FR) | 2018-05-03 | — | — | US | disclosed |
| WO-2016155906-A1 | NITRIC OXIDE DONATING DERIVATIVES OF FLUPROSTENOL | NICOX S.A. (FR) | 2016-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118677-A1 | NITRIC OXIDE DONATING DERIVATIVES OF FLUPROSTENOL | PTGIS, NOS2, PTGIR | FAAH 650/4885CNR1 766/4885CNR2 590/4885 |
| US-10280138-B2 | Nitric oxide donating derivatives of fluprostenol | PTGIS, NOS2, PTGIR | FAAH 650/4885CNR1 766/4885CNR2 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.