Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | STAT3 | P40763 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116056 | 0.95 | BACE1 (0.35) | KDM4ERENNR3C1LMNAL3MBTL1 | |
| SCHEMBL18116050 | 0.83 | LMNA (0.32) | KDM4ERENLMNAL3MBTL1PDE4A | |
| SCHEMBL22772346 | 0.80 | ALDH1A1 (0.35) | KDM4ELMNAL3MBTL1PDE4APDE4B | |
| SCHEMBL18116057 | 0.78 | PDE4A (0.33) | KDM4ERENLMNAL3MBTL1PDE4A | |
| SCHEMBL18116070 | 0.78 | LMNA (0.33) | KDM4ERENLMNAL3MBTL1PDE4A | |
| SCHEMBL22536766 | 0.71 | NCEH1 (0.33) | KDM4ELMNAPDE4APDE4BPDE4C | |
| SCHEMBL18116075 | 0.70 | MAOA (0.35) | KDM4ELMNAPDE4APDE4BPDE4C | |
| SCHEMBL22536765 | 0.69 | NCEH1 (0.36) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18116053 | 0.69 | EGFR (0.34) | KDM4ELMNAPDE4APDE4BPDE4C | |
| SCHEMBL22536823 | 0.67 | SLC2A1 (0.34) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274346-A1 | WATER-SOLUBLE PRODRUGS | Boston Biomedical, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016157052-A1 | WATER-SOLUBLE PRODRUGS | BOSTON BIOMEDICAL, INC. (US) | 2016-10-06 | — | — | WO | disclosed |