Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017561 | 0.92 | DHODH (0.61) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6655226 | 0.86 | DHODH (0.70) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27242987 | 0.86 | DHODH (0.74) | DHODHSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5049041 | 0.86 | DHODH (0.70) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL16741993 | 0.86 | DHODH (0.70) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL25813258 | 0.86 | DHODH (0.74) | DHODHSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL15196662 | 0.85 | DHODH (0.62) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8678233 | 0.84 | DHODH (0.68) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8678230 | 0.84 | DHODH (0.68) | DHODHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8614000 | 0.84 | DHODH (0.68) | DHODHSMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226007-A1 | NANOPARTICULATE COMPOSITION | ALGIAX PHARMACEUTICALS GMBH (DE) | 2023-07-20 | — | — | US | disclosed |
| US-20160287549-A1 | NOVEL METHODS FOR TREATING NEURODEGENERATIVE DISEASES | GENZYME CORPORATION | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226007-A1 | NANOPARTICULATE COMPOSITION | CRYAA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SFN | DHODH 4303/4885SMN1; SMN2 956/4885NPC1 1223/4885 |
| US-20160287549-A1 | NOVEL METHODS FOR TREATING NEURODEGENERATIVE DISEASES | DHODH, DLD, HAGH | DHODH 1/4885SMN1; SMN2 25/4885NPC1 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.