Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122013 | 0.95 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL28743533 | 0.86 | NPC1 (0.57) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL185735 | 0.86 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL10013448 | 0.84 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| Bromide SCHEMBL11463626 | 0.84 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL186863 | 0.84 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL6508240 | 0.83 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL15090535 | 0.82 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL10013484 | 0.81 | HSD17B1 (0.45) | HSD17B1HSD17B2CYP3A4CYP2C9KDR | |
| SCHEMBL3459364 | 0.81 | HSD17B1 (0.54) | HSD17B1HSD17B2CYP3A4CYP2C9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136403-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |
| US-20170217974-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
| US-20160289212-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2016-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289212-A1 | HEPATITIS B ANTIVIRAL AGENTS | ZC3HAV1, HAVCR2, SLC10A1 | HSD17B1 949/4885HSD17B2 2072/4885CYP3A4 429/4885 |
| US-20170217974-A1 | HEPATITIS B ANTIVIRAL AGENTS | HAVCR2, ZC3HAV1, SLC10A1 | HSD17B1 982/4885HSD17B2 1718/4885CYP3A4 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.