Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | HPGDS | O60760 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013448 | 0.98 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL186863 | 0.98 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| Bromide SCHEMBL11463626 | 0.98 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL15090535 | 0.96 | HSD17B1 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL15090492 | 0.93 | HSD17B1 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL23212803 | 0.90 | HPGDS (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL9958606 | 0.89 | HSD17B1 (0.51) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL28743533 | 0.89 | NPC1 (0.57) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL31312542 | 0.89 | HSD17B1 (0.53) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 | |
| SCHEMBL20379368 | 0.89 | HSD17B1 (0.53) | HSD17B1HSD17B2CYP3A4CYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190421-A2 | 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-DEPENDENT DISEASES | Universität des Saarlandes (DE) | 2010-06-02 | — | — | EP | claimed |
| WO-2009027346-A2 | 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-DEPENDENT DISEASES | Universität des Saarlandes (DE) | 2009-03-05 | — | — | WO | claimed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | claimed |
| US-11968893-B2 | Electroluminescent device | UDC IRELAND LIMITED (IE) | 2024-04-23 | — | — | US | disclosed |
| US-20220216422-A1 | Electroluminescent Device | UDC IRELAND LTD (IE) | 2022-07-07 | — | — | US | disclosed |
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2022-05-31 | — | — | US | disclosed |
| CN-109705012-B | Preparation method of 2, 5-diaryl five-membered heterocyclic aromatic hydrocarbon | 西北师范大学 | 2022-04-05 | — | — | CN | disclosed |
| EP-2315502-B1 | Electroluminescent device | UDC IRELAND LTD (IE) | 2020-10-14 | — | — | EP | disclosed |
| US-10454038-B2 | Delayed-fluorescence material and organic electroluminescence element using same | KYULUX, INC. (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20190237675-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2019-06-13 | — | — | US | disclosed |
| EP-0107599-B1 | PROCESS FOR THE PREPARATION OF SATURATED LINEAR ESTERS BY CARBONYLATION OF MONOOLEFINIC COMPOUNDS | RHONE-POULENC CHIMIE DE BASE (FR) | 1985-12-11 | — | — | EP | disclosed |
| EP-0107599-A1 | Process for the preparation of saturated linear esters by carbonylation of monoolefinic compounds | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-05-02 | — | — | EP | disclosed |
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4164480-A | POLYMER STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-08-14 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4105631-A | MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-4043973-A | PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS | EASTMAN KODAK COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3939115-A | OXADIAZOLES | EASTMAN KODAK COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
| US-3936419-A | Multichromophoric ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177306-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | TYR, LEF1, EFNA1 | HSD17B1 2485/4885HSD17B2 2415/4885CYP3A4 382/4885 |
| US-20220216422-A1 | Electroluminescent Device | PNPO, ODC1, AXL | HSD17B1 4485/4885HSD17B2 4363/4885CYP3A4 2357/4885 |
| US-10454038-B2 | Delayed-fluorescence material and organic electroluminescence element using same | HNRNPF, RABL6, SRSF6 | HSD17B1 4787/4885HSD17B2 4712/4885CYP3A4 3443/4885 |
| US-11345686-B2 | Aromatic amine derivative, and organic electroluminescent element | TYR, LEF1, EFNA1 | HSD17B1 2485/4885HSD17B2 2415/4885CYP3A4 382/4885 |
| US-11968893-B2 | Electroluminescent device | PNPO, ODC1, AXL | HSD17B1 4485/4885HSD17B2 4363/4885CYP3A4 2357/4885 |
| US-20190237675-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | TYR, NLRP1, NLRP3 | HSD17B1 2729/4885HSD17B2 2120/4885CYP3A4 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.