SCHEMBL18123748

SCHEMBL18123748

CC(C)CNC(=O)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.43
KMT2A Q03164 3/20 0.41
HSD17B10 Q99714 2/20 0.41
GAA P10253 1/20 0.41
MLYCD O95822 1/20 0.41
MAOB P27338 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11253426 0.76 LMNA (0.53) CTSLLMNAPOLBKMT2AGAA
SCHEMBL29502276 0.76 HPGD (0.44) LMNASMN1; SMN2
SCHEMBL190958 0.70 GAA (0.50) LMNAPOLBKMT2AGAATSHR
SCHEMBL162587 0.70 TP53 (0.44) LMNAPOLBKMT2AHSD17B10GAA
SCHEMBL18082339 0.70 MAPT (0.60) KMT2AALDH1A1MEN1SMN1; SMN2
Isoorotic Acid Methyl Ester SCHEMBL7487788 0.69 GAA (0.53) LMNAKMT2AGAAALDH1A1
SCHEMBL12050193 0.69 GAA (0.45) CTSLLMNAPOLBKMT2AGAA
Dimethylamine SCHEMBL1524840 0.69 KDM3B (0.56) CTSLLMNAPOLBKMT2AHSD17B10
SCHEMBL10824795 0.69 ALDH1A1 (0.43) LMNAKMT2AHSD17B10GAAALDH1A1
SCHEMBL27606923 0.69 LMNA (0.49) CTSLLMNAPOLBKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114645051-A Secretory immunoglobulin A (sIgA) binding nucleic acid molecule, sensor for sIgA analysis, and sIgA analysis method 日本电气方案创新株式会社 2022-06-21 CN disclosed
CN-109715807-B Secretory immunoglobulin A (sIgA) -binding nucleic acid molecule, sensor for sIgA analysis, and sIgA analysis method 日本电气方案创新株式会社 2022-05-17 CN disclosed
CN-109715644-B Nucleoside derivative or salt thereof, polynucleotide synthesis reagent, polynucleotide production method, polynucleotide, and bound nucleic acid molecule production method 日本电气方案创新株式会社 2022-03-22 CN disclosed
CN-109715645-B Nucleoside derivative or salt thereof, polynucleotide synthesis reagent, polynucleotide production method, polynucleotide, and bound nucleic acid molecule production method 日本电气方案创新株式会社 2022-03-22 CN disclosed
US-11236342-B2 Secretory immunoglobulin a (sIgA)-binding nucleic acid molecule, sIgA analysis sensor, and sIgA analysis method NEC SOLUTION INNOVATORS, LTD. (JP) 2022-02-01 US disclosed
EP-3783105-B1 SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA NEC SOLUTION INNOVATORS LTD (JP) 2021-11-03 EP disclosed
EP-3514237-B1 SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA NEC SOLUTION INNOVATORS LTD (JP) 2021-07-14 EP disclosed
EP-3514165-B1 NUCLEOSIDE DERIVATIVE OR SALT THEREOF, REAGENT FOR SYNTHESIZING POLYNUCLEOTIDE, METHOD FOR PRODUCING POLYNUCLEOTIDE, POLYNUCLEOTIDE, AND METHOD FOR PRODUCING BINDING NUCLEIC ACID MOLECULE NEC SOLUTION INNOVATORS LTD (JP) 2021-05-19 EP disclosed
US-10934548-B2 Wheat allergen-binding nucleic acid molecule and use thereof NEC SOLUTION INNOVATORS, LTD. (JP) 2021-03-02 US disclosed
EP-3783105-A1 SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA NEC Solution Innovators, Ltd. (JP) 2021-02-24 EP disclosed
US-20190211048-A1 NUCLEOSIDE DERIVATIVE OR SALT THEREOF, POLYNUCLEOTIDE SYNTHESIS REAGENT, METHOD FOR PRODUCING POLYNUCLEOTIDE, POLYNUCLEOTIDE, AND METHOD FOR PRODUCING BINDING NUCLEIC ACID MOLECULE NEC SOLUTION INNOVATORS, LTD. (JP) 2019-07-11 US disclosed
EP-3078747-B1 PEANUT-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF NEC SOLUTION INNOVATORS LTD (JP) 2019-05-15 EP disclosed
US-20190071735-A1 TARGET ANALYSIS METHOD AND TARGET ANALYSIS KIT FOR USE IN THE METHOD NEC SOLUTION INNOVATORS, LTD. (JP) 2019-03-07 US disclosed
EP-3406735-A1 TARGET ANALYSIS METHOD AND TARGET ANALYSIS KIT FOR USE IN SAID METHOD NEC Solution Innovators, Ltd. (JP) 2018-11-28 EP disclosed
US-20180327746-A1 Alpha-AMYLASE-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF NEC SOLUTION INNOVATORS, LTD. (JP) 2018-11-15 US disclosed
EP-3378939-A1 WHEAT ALLERGEN-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF NEC Solution Innovators, Ltd. (JP) 2018-09-26 EP disclosed
US-9790508-B2 Peanut-binding nucleic acid molecule and use thereof NEC SOLUTION INNOVATORS, LTD. (JP) 2017-10-17 US disclosed
US-20160298117-A1 PEANUT-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF NEC SOLUTION INNOVATORS, LTD. (JP) 2016-10-13 US disclosed
EP-3078747-A1 PEANUT-BINDING NUCLEIC ACID MOLECULE AND USE THEREOF NEC Solution Innovators, Ltd. (JP) 2016-10-12 EP disclosed
CN-105814206-A Peanut-binding nucleic acid molecules and uses thereof 日本电气方案创新株式会社 2016-07-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10934548-B2 Wheat allergen-binding nucleic acid molecule and use thereof NOS1, NOS2, MICA CTSL 3971/4885LMNA 2725/4885POLB 374/4885
US-20190211048-A1 NUCLEOSIDE DERIVATIVE OR SALT THEREOF, POLYNUCLEOTIDE SYNTHESIS REAGENT, METHOD FOR PRODUCING POLYNUCLEOTIDE, POLYNUCLEOTIDE, AND METHOD FOR PRODUCING BINDING NUCLEIC ACID MOLECULE SNRPA1, SNRPB2, NSUN3 CTSL 4786/4885LMNA 798/4885POLB 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.