Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PROKR2 | Q8NFJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354108 | 0.84 | TAAR1 (0.41) | MAPK8LARS1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27246692 | 0.82 | TAAR1 (0.40) | MAPK8LARS1CSNK2A1NPC1RAB9A | |
| SCHEMBL20563584 | 0.79 | TAAR1 (0.44) | MAPK8LARS1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL565394 | 0.72 | PROKR2 (0.44) | MAPK8NPC1RAB9ASMN1; SMN2PROKR2 | |
| SCHEMBL111534 | 0.72 | TAAR1 (0.52) | NPC1RAB9ASMN1; SMN2CD274 | |
| SCHEMBL565128 | 0.70 | MAPK8 (0.38) | MAPK8NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL29859704 | 0.69 | ALDH1A1 (0.53) | SMN1; SMN2CD274 | |
| SCHEMBL14907127 | 0.69 | TTR (0.44) | MAPK8NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL18397104 | 0.69 | ALDH1A1 (0.53) | SMN1; SMN2CD274 | |
| SCHEMBL13284746 | 0.68 | PROKR2 (0.45) | MAPK8NPC1RAB9ASMN1; SMN2PROKR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | Prosetta Antiviral ,Inc. | 2018-05-03 | — | — | US | disclosed |
| WO-2016161021-A1 | N-METHYL PYRAZOLES | Prosetta Antiviral, Inc. (US) | 2016-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | ZC3HAV1, MAVS, NNMT | MAPK8 3206/4885LARS1 2567/4885CSNK2A1 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.