SCHEMBL224923

SCHEMBL224923

Clc1ccc(Cl)c(SSc2cc(Cl)ccc2Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.52
CYP3A4 P08684 5/20 0.46
HSD17B10 Q99714 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 4/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.46
CYP2C9 P11712 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP2C19 P33261 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2D6 P10635 2/20 0.46
PLA2G1B P04054 1/20 0.46
HSP90AA1 P07900 1/20 0.46
HIF1A Q16665 1/20 0.46
ATG4B Q9Y4P1 1/20 0.46
TSHR P16473 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
RHEB Q15382 1/20 0.42
FBP1 P09467 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7268486 0.83 HPGD (0.58) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL10940318 0.81 TP53 (0.50) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL27923372 0.79 TP53 (0.48) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL1145559 0.79 TP53 (0.48) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL19872417 0.79 ALDH1A1 (0.48) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL1145555 0.79 TP53 (0.48) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL224671 0.78 FBP1 (0.58) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL30472043 0.78 FBP1 (0.58) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL7263092 0.76 CYP3A4 (0.44) TP53CYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL8779725 0.75 TP53 (0.44) TP53CYP3A4HSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-4072584-A PIGMENTS, RUBBER ALLIED CHEMICAL CORPORATION (US) 1978-02-07 US claimed
JP-10080503-A None JP disclosed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
US-20260027422-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-29 US disclosed
US-4128586-A Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols ALLIED CHEMICAL CORPORATION (US) 1978-12-05 US disclosed
US-4100276-A BACTERICIDES, MICROBIOCIDES LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1978-07-11 US disclosed
US-4072584-A PIGMENTS, RUBBER ALLIED CHEMICAL CORPORATION (US) 1978-02-07 US disclosed
US-4069259-A Process for preparing organic disulfides ALLIED CHEMICAL CORPORATION (US) 1978-01-17 US disclosed
US-4060606-A 16-SULFIDES OR SULFOXIDES, STEROIDS, ANTIBACTERIAL LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1977-11-29 US disclosed
US-4056581-A Process for the preparation of phosphorodichloridothiolates ROHM AND HAAS COMPANY (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027422-A1 GOLF BALL KIF5A, KIF5C, SURF4 TP53 4319/4885CYP3A4 3943/4885HSD17B10 584/4885
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 TP53 4290/4885CYP3A4 4185/4885HSD17B10 707/4885
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 TP53 2562/4885CYP3A4 4002/4885HSD17B10 1594/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 TP53 4484/4885CYP3A4 2613/4885HSD17B10 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.