SCHEMBL18134367

SCHEMBL18134367

CC1(C)OC(c2ccc(-c3ccc(-c4ccc(-c5ccccc5)cc4)cc3)cc2)OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
KDM1A O60341 3/20 0.39
MAOB P27338 1/20 0.39
CYP1A2 P05177 2/20 0.39
EPHX1 P07099 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.37
CYP2C19 P33261 2/20 0.37
KMT2A Q03164 2/20 0.37
TP53 P04637 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
BRD4 O60885 1/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNG P07510 1/20 0.35
CHRNB1 P11230 1/20 0.35
CHRNB2 P17787 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26434430 0.89 EPHX1 (0.39) LPLLIPGKDM1AMAOBCYP1A2
SCHEMBL28465752 0.89 ALDH1A1 (0.39) LPLLIPGKDM1AMAOBCYP1A2
SCHEMBL24452337 0.89 LPL (0.39) LPLLIPGKDM1AMAOBCYP1A2
SCHEMBL28475250 0.87 L3MBTL1 (0.46) LPLLIPGALDH1A1MEN1KMT2A
SCHEMBL9946121 0.87 MEN1 (0.46) KDM1AMAOBALDH1A1MEN1CYP2C19
SCHEMBL18134371 0.85 LPL (0.41) LPLLIPGCYP1A2MEN1KMT2A
SCHEMBL17863581 0.84 MAPK1 (0.37) MEN1CYP2C19KMT2AMAPK1
SCHEMBL18371209 0.83 LPL (0.40) LPLLIPGMEN1KMT2A
SCHEMBL18371213 0.83 LPL (0.40) LPLLIPGMEN1KMT2A
SCHEMBL18371205 0.82 SLC5A2 (0.40) LPLLIPGKDM1AMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-10-13 US disclosed
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160301012-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 LPL 1970/4885LIPG 1944/4885KDM1A 2281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.