SCHEMBL28465752

SCHEMBL28465752

CC1(C)OC(c2ccc(Nc3ccc(-c4ccccc4)cc3)cc2)OC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
ALOX12 P18054 4/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 2/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
PTGS2 P35354 1/20 0.39
HTR2B P41595 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
HPGD P15428 2/20 0.37
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18134367 0.89 LPL (0.46) ALDH1A1MAPK1SLC6A2LPLLIPG
SCHEMBL24452337 0.80 LPL (0.39) ALDH1A1L3MBTL1TDP1SLC6A2LPL
SCHEMBL26434430 0.80 EPHX1 (0.39) MAPK1PTGS2LPLLIPGKDM1A
SCHEMBL28475250 0.78 L3MBTL1 (0.46) ALDH1A1L3MBTL1MAPK1LPLLIPG
SCHEMBL18134371 0.76 LPL (0.41) HTR2BLPLLIPGMEN1KMT2A
SCHEMBL15392903 0.76 HSD17B10 (0.41) ALDH1A1ALOX12L3MBTL1ALOX15HSD17B10
SCHEMBL18371213 0.75 LPL (0.40) HTR2BLPLLIPGMEN1KMT2A
SCHEMBL18371205 0.74 SLC5A2 (0.40) ALDH1A1HTR2BLPLLIPGMEN1
SCHEMBL18371207 0.73 LPL (0.39) HTR2BLPLLIPGMEN1KMT2A
SCHEMBL68489 0.73 ALDH1A1 (0.71) ALDH1A1ALOX12L3MBTL1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868956-A Light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-10-30 CN disclosed