Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 3/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16826079 | 0.93 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ACHEHTT | |
| SCHEMBL16825838 | 0.82 | KDM4E (0.41) | CHIT1CHIAKDM4EMEN1KMT2A | |
| SCHEMBL16825723 | 0.74 | CHIA (0.38) | SLC6A4SLC6A3ACHECHIT1CHIA | |
| SCHEMBL16825857 | 0.74 | HTR1A (0.55) | SLC6A3NPSR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL16825854 | 0.73 | CHIA (0.37) | SLC6A4SLC6A3ACHECHIT1CHIA | |
| SCHEMBL16826354 | 0.72 | CHIA (0.59) | CHIT1CHIAMEN1KMT2AALDH1A1 | |
| SCHEMBL16826407 | 0.72 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL16826410 | 0.71 | GAA (0.62) | HTTNPSR1GAAKDM4EMEN1 | |
| SCHEMBL14027394 | 0.70 | ALDH1A1 (0.63) | SLC6A3HTTNPSR1GAAKDM4E | |
| SCHEMBL16826072 | 0.69 | CHIT1 (0.43) | SLC6A2SLC6A4SLC6A3ACHECHIT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | SLC6A2 1970/4885SLC6A4 1877/4885SLC6A3 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.