Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498167 | 0.94 | GAA (0.49) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18227188 | 0.91 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL136250 | 0.88 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL344303 | 0.84 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1920842 | 0.83 | L3MBTL1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16460026 | 0.83 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9470658 | 0.83 | SYK (0.51) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7306620 | 0.83 | LMNA (0.57) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10663138 | 0.81 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6502340 | 0.80 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115746732-A | Low-temperature reworked foam adhesive tape and preparation method thereof | 苏州世华新材料科技股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-7935831-B2 | Process for the preparation of 2-azabicyclo[3.3.0]octane-3-carboxylic Acid Derivatives | EVONIK DEGUSSA GMBH (DE) | 2011-05-03 | — | — | US | disclosed |
| CN-101146771-B | Process for preparing 2-azabicyclo- [3.3.0] octane-3-carboxylic acid derivatives | DEGUSSA | 2011-04-13 | — | — | CN | disclosed |
| US-20090306404-A1 | Process for the Preparation of 2-azabicyclo[3.3.0]octane-3-carboxylic Acid Derivatives | DEGUSSA GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1861368-B1 | PROCESS FOR THE PREPARATION OF 2-AZABICYCLOÝ3.3.0¨OCTANE-3-CARBOXYLIC ACID DERIVATIVES | EVONIK DEGUSSA GMBH (DE) | 2009-02-18 | — | — | EP | disclosed |
| CN-101146771-A | Process for preparing 2-azabicyclo- [3.3.0] octane-3-carboxylic acid derivatives | DEGUSSA (DE) | 2008-03-19 | — | — | CN | disclosed |
| EP-1861368-A1 | PROCESS FOR THE PREPARATION OF 2-AZABICYCLOÝ3.3.0¨OCTANE-3-CARBOXYLIC ACID DERIVATIVES | Evonik Degussa GmbH (DE) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100168-A1 | PROCESS FOR THE PREPARATION OF 2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLIC ACID DERIVATIVES | DEGUSSA GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306404-A1 | Process for the Preparation of 2-azabicyclo[3.3.0]octane-3-carboxylic Acid Derivatives | AZI2, CYP11B2, CYP51A1 | NPC1 3284/4885RAB9A 1803/4885SMN1; SMN2 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.