Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25677919 | 0.78 | CA2 (0.51) | ALDH1A1GAAHSD17B10HTTKMT2A | |
| SCHEMBL25678287 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10HTTKMT2A | |
| SCHEMBL25677914 | 0.71 | HPGDS (0.46) | ALDH1A1GAAHSD17B10HTTCA2 | |
| SCHEMBL7403097 | 0.71 | PPARG (0.51) | ALDH1A1HSD17B10KMT2AITGA4ITGB7 | |
| Hydrochloric Acid SCHEMBL27563726 | 0.70 | CA1 (0.56) | ALDH1A1GAAHSD17B10HTTKMT2A | |
| SCHEMBL25678196 | 0.68 | NPC1 (0.44) | ALDH1A1GAAHSD17B10HTTROCK2 | |
| SCHEMBL5682928 | 0.68 | HTT (0.66) | ALDH1A1GAAHSD17B10HTTCA2 | |
| SCHEMBL5681701 | 0.68 | HTT (0.87) | ALDH1A1GAAHSD17B10HTTPOLB | |
| SCHEMBL11900633 | 0.67 | KMT2A (0.65) | ALDH1A1GAAHSD17B10KMT2ANR1H4 | |
| SCHEMBL9698029 | 0.66 | TSHR (0.47) | ALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160296523-A1 | Sirtuin Modulators as Inhibitors of Cytomegalovirus | THE TRUSTEES OF PRINCETON UNIVERSITY | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296523-A1 | Sirtuin Modulators as Inhibitors of Cytomegalovirus | SIRT1, SIRT2, SIRT7 | ALDH1A1 2630/4885GAA 1289/4885HSD17B10 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.