Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753654 | 0.80 | L3MBTL1 (0.42) | L3MBTL1MAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20276702 | 0.79 | LMNA (0.47) | BRD9IRAK4GSK3BDYRK1ALMNA | |
| SCHEMBL22857997 | 0.78 | CNR2 (0.53) | L3MBTL1KMT2ABRD9IRAK4GSK3B | |
| SCHEMBL31437491 | 0.77 | LMNA (0.40) | BRD9IRAK4GSK3BDYRK1ALMNA | |
| SCHEMBL20262443 | 0.77 | IRAK4 (0.41) | BRD9IRAK4GSK3BDYRK1ALMNA | |
| SCHEMBL22857998 | 0.76 | IRAK4 (0.45) | L3MBTL1BRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL27457954 | 0.75 | GSK3B (0.40) | BRD9IRAK4GSK3BDYRK1ALMNA | |
| SCHEMBL27457955 | 0.75 | ATR (0.39) | BRD9IRAK4GSK3BDYRK1ALMNA | |
| SCHEMBL31439890 | 0.74 | GSK3B (0.39) | ALDH1A1BRD9IRAK4GSK3BDYRK1A | |
| SCHEMBL31555029 | 0.74 | IRAK4 (0.41) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |