Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138351 | 0.85 | PRMT1 (0.36) | L3MBTL1PRMT1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL18131172 | 0.83 | PRMT1 (0.36) | L3MBTL1PRMT1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL18138228 | 0.83 | LMNA (0.37) | L3MBTL1LMNAPRMT1ALDH1A1MEN1 | |
| SCHEMBL18138300 | 0.83 | PRMT1 (0.35) | L3MBTL1LMNAPRMT1CYP1A2CYP2C19 | |
| SCHEMBL18131303 | 0.82 | PRMT1 (0.36) | LMNAPRMT1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18138283 | 0.82 | PRMT1 (0.34) | L3MBTL1PRMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL18379692 | 0.81 | HTT (0.41) | L3MBTL1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18138290 | 0.81 | IRAK4 (0.35) | L3MBTL1LMNAPRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18138301 | 0.80 | ALDH1A1 (0.35) | L3MBTL1LMNAPRMT1ALDH1A1MEN1 | |
| SCHEMBL20555276 | 0.80 | GSK3B (0.39) | GSK3BDYRK1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110857300-B | Condensed ring triazole compounds, preparation method and application | 上海凌达生物医药有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-109721600-B | Nitrogen-containing fused ring compounds and preparation method and application thereof | 上海凌达生物医药有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-110857300-A | Condensed ring triazole compounds, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-03-03 | — | — | CN | disclosed |
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |