SCHEMBL18138722

SCHEMBL18138722

Cc1cc(N(C)c2ccccc2)c([N+](=O)[O-])cc1[N+]#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.45
▸ KMT2A Q03164 4/20 0.45
▸ MAPT P10636 7/20 0.39
▸ HSD17B10 Q99714 1/20 0.38
▸ ALDH1A1 P00352 5/20 0.36
▸ LMNA P02545 5/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.36
▸ HPGD P15428 3/20 0.36
▸ MAPK1 P28482 3/20 0.36
▸ S1PR4 O95977 1/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ S1PR1 P21453 1/20 0.36
▸ CCR6 P51684 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ TLR9 Q9NR96 1/20 0.36
▸ HCAR3 P49019 1/20 0.36
▸ VCAM1 P19320 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ GLA P06280 1/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18227143 0.84 ALDH1A1 (0.37) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL18138714 0.84 KMT2A (0.43) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL18138720 0.75 MEN1 (0.55) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL15236989 0.72 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL27659172 0.72 MEN1 (0.57) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL28468319 0.72 KMT2A (0.55) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL30641706 0.71 MEN1 (0.48) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL7403916 0.71 MEN1 (0.53) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL3518353 0.71 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL28455320 0.69 ALDH1A1 (0.51) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081581-B1 DIAZORESIN, PHOTORESIST COMPOSITION AND PREPARATION METHOD OF PHOTORESIST COMPOSITION BOE TECHNOLOGY GROUP CO LTD (CN) 2019-08-07 — — EP disclosed
US-10303053-B2 Diazo-resin, photoresist composition and method of preparing same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2019-05-28 — — US disclosed
US-20160334704-A1 DIAZO-RESIN, PHOTORESIST COMPOSITION AND METHOD OF PREPARING SAME BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-11-17 — — US disclosed
EP-3081581-A1 DIAZORESIN, PHOTORESIST COMPOSITION AND PREPARATION METHOD OF PHOTORESIST COMPOSITION BOE Technology Group Co., Ltd. (CN) 2016-10-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10303053-B2 Diazo-resin, photoresist composition and method of preparing same LCP1, CAD, CDH1 MEN1 3733/4885KMT2A 486/4885MAPT 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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