SCHEMBL18227143

SCHEMBL18227143

CCN(c1ccccc1)c1cc(C)c([N+]#N)cc1[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ HCAR3 P49019 3/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ MAPT P10636 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.36
▸ ALDH3A1 P30838 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ VCAM1 P19320 1/20 0.34
▸ CRHBP P24387 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ CRHR2 Q13324 1/20 0.33
▸ TLR9 Q9NR96 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ S1PR4 O95977 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18138722 0.84 MEN1 (0.45) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL18138717 0.80 HCAR3 (0.41) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL18138716 0.77 TSHR (0.47) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL18138718 0.74 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL11748283 0.73 KIF18A (0.48) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL11449805 0.69 HCAR3 (0.55) ALDH1A1SMN1; SMN2HCAR3MEN1KMT2A
SCHEMBL18138714 0.68 KMT2A (0.43) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL6831372 0.65 MEN1 (0.70) ALDH1A1MEN1KMT2AMAPTRAB9A
SCHEMBL5843017 0.65 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL1468921 0.65 CYP1A2 (0.56) ALDH1A1MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10303053-B2 Diazo-resin, photoresist composition and method of preparing same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2019-05-28 — — US disclosed
US-20160334704-A1 DIAZO-RESIN, PHOTORESIST COMPOSITION AND METHOD OF PREPARING SAME BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10303053-B2 Diazo-resin, photoresist composition and method of preparing same LCP1, CAD, CDH1 ALDH1A1 4410/4885SMN1; SMN2 1484/4885HCAR3 4150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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