SCHEMBL18146372

SCHEMBL18146372

CNC(=O)c1ccc(NC(=O)c2cc(N)ccc2Cl)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 4/20 0.47
▸ JAK2 O60674 2/20 0.46
▸ TYK2 P29597 1/20 0.46
▸ KDR P35968 1/20 0.46
▸ SCN10A Q9Y5Y9 1/20 0.45
▸ PPARG P37231 2/20 0.43
▸ BTK Q06187 1/20 0.43
▸ P4HTM Q9NXG6 1/20 0.43
▸ KCNQ3 O43525 1/20 0.43
▸ KCNQ2 O43526 1/20 0.43
▸ KCNE1 P15382 1/20 0.43
▸ KCNQ1 P51787 1/20 0.43
▸ BACE1 P56817 1/20 0.43
▸ PDGFRB P09619 1/20 0.43
▸ FGFR1 P11362 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ BRAF P15056 1/20 0.43
▸ EPHB4 P54760 1/20 0.43
▸ PTK2 Q05397 1/20 0.43
▸ MAPK14 Q16539 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18160291 0.86 CSF1R (0.50) CSF1RKDRPPARGP4HTM
SCHEMBL18147341 0.84 KCNQ3 (0.60) CSF1RJAK2TYK2PPARGKCNQ3
SCHEMBL21106289 0.82 JAK2 (0.48) CSF1RJAK2TYK2PPARGBTK
SCHEMBL18146141 0.81 SMN1; SMN2 (0.62) PPARGCYP2C9
SCHEMBL2303946 0.79 SMN1; SMN2 (0.54) JAK2TYK2KDRSCN10ACYP2C9
SCHEMBL18147752 0.79 PPARG (0.53) CSF1RJAK2TYK2SCN10APPARG
SCHEMBL21105533 0.78 PPARG (0.57) JAK2TYK2PPARGKCNQ3KCNQ2
SCHEMBL21105387 0.78 PPARG (0.44) CSF1RJAK2TYK2PPARGBTK
Hydrochloric Acid SCHEMBL23859231 0.78 SMN1; SMN2 (0.53) JAK2TYK2KDRSCN10ACYP2C9
SCHEMBL21118649 0.77 PTPN1 (0.58) CSF1RJAK2TYK2KDRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 — — EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 — — US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 — — US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 — — EP disclosed
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-01 — — US disclosed
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-03-25 — — US disclosed
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-01-09 — — US disclosed
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 — — US disclosed
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 — — US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 — — US disclosed
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-28 — — US disclosed
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-28 — — US disclosed
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-05 — — US disclosed
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-05 — — US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 — — US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 — — US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 — — US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 — — US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 — — US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885JAK2 2264/4885TYK2 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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