SCHEMBL18160291

SCHEMBL18160291

CNC(=O)c1ccc(NC(=O)c2cc(C)ccc2Cl)cn1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 7/20 0.50
▸ P4HTM Q9NXG6 1/20 0.50
▸ KDR P35968 1/20 0.47
▸ LMNA P02545 3/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ GCGR P47871 1/20 0.44
▸ PPARG P37231 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18146372 0.86 CSF1R (0.47) CSF1RP4HTMKDRPPARG
SCHEMBL18160402 0.85 KCNQ3 (0.60) CSF1RLMNAALDH1A1KDM4ESMN1; SMN2
SCHEMBL18146141 0.82 SMN1; SMN2 (0.62) LMNAMEN1KMT2ASMN1; SMN2PPARG
SCHEMBL18160286 0.80 PPARG (0.53) CSF1RLMNAALDH1A1KDM4EMEN1
SCHEMBL12900908 0.79 SMN1; SMN2 (0.55) LMNAALDH1A1KDM4EMEN1KMT2A
SCHEMBL18160382 0.78 F10 (0.62) LMNAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL18160306 0.78 HDAC8 (0.68) LMNAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL22227949 0.77 P4HTM (0.55) P4HTMKDRLMNAALDH1A1KDM4E
SCHEMBL18160285 0.76 CSF1R (0.74) CSF1RALDH1A1
SCHEMBL18160302 0.75 TYK2 (0.73) CSF1RMEN1KMT2ASMN1; SMN2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 — — US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD CSF1R 4210/4885P4HTM 2825/4885KDR 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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