SCHEMBL18147341

SCHEMBL18147341

Nc1ccc(Cl)c(C(=O)Nc2ccc(Cl)nc2)c1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KCNQ3 O43525 15/20 0.60
▸ KCNQ2 O43526 15/20 0.60
▸ KCNE1 P15382 11/20 0.60
▸ KCNQ1 P51787 11/20 0.60
▸ BACE1 P56817 1/20 0.52
▸ JAK2 O60674 1/20 0.50
▸ TYK2 P29597 1/20 0.50
▸ CSF1R P07333 2/20 0.47
▸ PPARG P37231 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21106289 0.86 JAK2 (0.48) KCNQ3KCNQ2KCNE1KCNQ1JAK2
SCHEMBL18146372 0.84 CSF1R (0.47) KCNQ3KCNQ2KCNE1KCNQ1BACE1
SCHEMBL18160402 0.83 KCNQ3 (0.60) KCNQ3KCNQ2KCNE1KCNQ1BACE1
SCHEMBL18147752 0.83 PPARG (0.53) KCNQ3KCNQ2KCNE1KCNQ1JAK2
SCHEMBL21105533 0.82 PPARG (0.57) KCNQ3KCNQ2JAK2TYK2PPARG
SCHEMBL21105387 0.82 PPARG (0.44) KCNQ3KCNQ2KCNE1KCNQ1JAK2
SCHEMBL21106244 0.81 PPARG (0.51) JAK2TYK2CSF1RPPARG
SCHEMBL21105452 0.81 PPARG (0.71) JAK2TYK2CSF1RPPARG
SCHEMBL21118649 0.81 PTPN1 (0.58) KCNQ3KCNQ2KCNE1KCNQ1BACE1
SCHEMBL3441208 0.81 MAPK1 (0.56) JAK2TYK2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 — — EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 — — US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 — — US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 — — EP disclosed
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-01 — — US disclosed
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-03-25 — — US disclosed
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-01-09 — — US disclosed
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 — — US disclosed
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 — — US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 — — US disclosed
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-28 — — US disclosed
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-28 — — US disclosed
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-05 — — US disclosed
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-05 — — US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 — — US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 — — US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 — — US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 — — US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 — — US disclosed
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20160304522-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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