Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 12/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 12/20 | 0.60 |
| ▸ | KCNE1 | P15382 | 9/20 | 0.60 |
| ▸ | KCNQ1 | P51787 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 4/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363248 | 0.88 | RAB9A (0.57) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL18160291 | 0.85 | CSF1R (0.50) | SMN1; SMN2CSF1RLMNAKDM4EALDH1A1 | |
| SCHEMBL18147341 | 0.83 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNE1KCNQ1CSF1R | |
| SCHEMBL18160286 | 0.83 | PPARG (0.53) | KCNQ3KCNQ2CSF1RLMNAKDM4E | |
| SCHEMBL18160382 | 0.81 | F10 (0.62) | RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18160306 | 0.81 | HDAC8 (0.68) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13947174 | 0.80 | RAB9A (0.83) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL18160285 | 0.80 | CSF1R (0.74) | CSF1RALDH1A1 | |
| SCHEMBL7129113 | 0.79 | SMN1; SMN2 (0.67) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL18160302 | 0.78 | TYK2 (0.73) | SMN1; SMN2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304522-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885 |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | KCNQ3 1190/4885KCNQ2 1235/4885KCNE1 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.