Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492088 | 0.83 | NPC1 (0.42) | KDM4EALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL27849935 | 0.73 | ROCK1 (0.40) | KDM4EALDH1A1MAPTTSHRCA1 | |
| SCHEMBL27836302 | 0.73 | KDM4E (0.38) | KDM4EALOX12TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27690392 | 0.72 | KMO (0.46) | — | |
| SCHEMBL8847325 | 0.71 | TSHR (0.42) | KDM4EALOX12TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28776179 | 0.71 | SORD (0.32) | KDM4EALOX12 | |
| SCHEMBL29622864 | 0.70 | KDM4E (0.50) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL34548 | 0.70 | KDM4E (0.50) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27710393 | 0.69 | KMO (0.33) | KDM4EL3MBTL1KDM5C | |
| SCHEMBL3467794 | 0.69 | FFAR1 (0.36) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110123877-A1 | CATALYST FOR OXYGEN REDUCTION ELECTRODE AND OXYGEN REDUCTION ELECTRODE | NEC CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |