Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347714 | 0.79 | SMN1; SMN2 (0.35) | SORD | |
| SCHEMBL27849935 | 0.76 | ROCK1 (0.40) | KDM4E | |
| SCHEMBL27836302 | 0.72 | KDM4E (0.38) | KDM4EALOX12 | |
| SCHEMBL27690392 | 0.71 | KMO (0.46) | — | |
| SCHEMBL1814987 | 0.71 | KDM4E (0.38) | KDM4EALOX12 | |
| SCHEMBL27710393 | 0.68 | KMO (0.33) | KDM4E | |
| SCHEMBL27367334 | 0.68 | CYP2C9 (0.30) | — | |
| SCHEMBL3467794 | 0.68 | FFAR1 (0.36) | KDM4E | |
| SCHEMBL27714516 | 0.67 | PSMD14 (0.30) | — | |
| SCHEMBL27492088 | 0.67 | NPC1 (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448844-B | Thiazolo-pyramidine / pyridine urea derivatives as adenosine a2b receptor antagonists | HOFFMANN LA ROCHE | 2012-07-25 | — | — | CN | disclosed |
| CN-101448844-A | Thiazolo-pyramidine / pyridine urea derivatives as adenosine a2b receptor antagonists | HOFFMANN LA ROCHE (CH) | 2009-06-03 | — | — | CN | disclosed |