Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814987 | 0.83 | KDM4E (0.38) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL5352445 | 0.82 | L3MBTL1 (0.44) | COMTKDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL28545192 | 0.78 | ATM (0.39) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL27690392 | 0.72 | KMO (0.46) | — | |
| SCHEMBL5426681 | 0.71 | COMT (0.43) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL1163789 | 0.71 | NPC1 (0.49) | NPC1RAB9ACOMTKMT2AMEN1 | |
| SCHEMBL696116 | 0.70 | XDH (0.50) | COMTKMT2AMEN1SMOKDM4E | |
| SCHEMBL190954 | 0.70 | AURKA (0.63) | NPC1RAB9AKMT2AMEN1SMO | |
| SCHEMBL29620532 | 0.70 | AURKA (0.63) | NPC1RAB9AKMT2AMEN1SMO | |
| SCHEMBL27849935 | 0.69 | ROCK1 (0.40) | KDM4EMAPTTSHRALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161342-C | Process for preparing substituted pyrimidines | �����ɷ� | 2004-08-11 | — | — | CN | disclosed |
| CN-1355792-A | process for preparation of substituted pyrimidines | BASF AG (DE) | 2002-06-26 | — | — | CN | disclosed |