Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1833787 | 0.87 | GABRP (0.62) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL19327226 | 0.84 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL27563645 | 0.83 | GABRP (0.65) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL7086022 | 0.83 | GABRP (0.65) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| SCHEMBL14054474 | 0.82 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL8062635 | 0.82 | GABRP (0.56) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL27521490 | 0.82 | GABRP (0.56) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL7752977 | 0.81 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL28729193 | 0.81 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRP | |
| Succinic Acid SCHEMBL28156291 | 0.81 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304912-A1 | A PROCESS FOR PREPARING SUCCINATE ESTER | MYRIANT CORPORATION (US) | 2016-10-20 | — | — | US | disclosed |