Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16420391 | 0.76 | — | — | |
| SCHEMBL16420393 | 0.76 | GPR84 (0.32) | — | |
| SCHEMBL8263867 | 0.76 | PARP1 (0.31) | — | |
| SCHEMBL9449696 | 0.73 | CCR5 (0.30) | — | |
| SCHEMBL8263271 | 0.72 | PARP1 (0.34) | — | |
| SCHEMBL17144450 | 0.72 | ADRA1A (0.37) | — | |
| SCHEMBL23782700 | 0.68 | ADRA1A (0.37) | — | |
| SCHEMBL17143956 | 0.67 | HTR2A (0.37) | BCL2L1 | |
| SCHEMBL10802712 | 0.67 | BCL2L1 (0.50) | BCL2L1BADAR | |
| SCHEMBL29439671 | 0.63 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283464-A1 | FACTOR XIa INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168098-A1 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-10-20 | — | — | WO | disclosed |