SCHEMBL18153355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18153416	0.90	CASP1 (0.61)	LMNAMAPTBPTFNPSR1ALDH1A1
	SCHEMBL3246321	0.88	CASP1 (0.59)	LMNAMAPTSMN1; SMN2BPTFALDH1A1
	SCHEMBL18063516	0.82	LMNA (0.72)	LMNAMAPTBPTFMAPK1TAAR1
	SCHEMBL3245932	0.80	GALR2 (0.61)	LMNAMAPTSMN1; SMN2NPSR1GAA
	SCHEMBL18153318	0.80	BPTF (0.65)	LMNAMAPTBPTFROCK2CASP1
	SCHEMBL9069830	0.80	CASP1 (0.71)	SMN1; SMN2POLBNPSR1KMT2AKDM4E
	SCHEMBL23321038	0.80	MAPT (0.77)	LMNAMAPTSMN1; SMN2CYP1A2CYP3A4
	SCHEMBL17673690	0.80	MAPT (0.77)	LMNAMAPTSMN1; SMN2CYP1A2CYP3A4
	SCHEMBL18153389	0.80	ROCK2 (0.56)	LMNAMAPTSMN1; SMN2CYP1A2CYP3A4
	SCHEMBL18063486	0.79	LMNA (0.54)	LMNAMAPTSMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.