Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18162440 | 0.87 | JAK2 (0.41) | ABCG2LMNAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL18162582 | 0.85 | ABCG2 (0.47) | ABCG2LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL20042169 | 0.80 | ABCG2 (0.47) | ABCG2LMNAMAPTHSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL18153287 | 0.79 | ABCG2 (0.47) | ABCG2LMNAMAPTHSD17B10ALOX15 | |
| SCHEMBL20042138 | 0.79 | MAPT (0.47) | ABCG2LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL23221570 | 0.76 | MAPT (0.44) | ABCG2LMNAMAPTCCNE1CDK2 | |
| SCHEMBL18162488 | 0.76 | CCR6 (0.49) | ABCG2LMNAMAPTHSD17B10CCNE1 | |
| SCHEMBL18153360 | 0.74 | GPR119 (0.48) | ABCG2LMNAMAPTHSD17B10KDM4E | |
| SCHEMBL18153314 | 0.72 | LMNA (0.66) | LMNAMAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL18153406 | 0.72 | ROCK2 (0.62) | ABCG2LMNAMAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |