Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.58 |
| ▸ | CDK2 | P24941 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153366 | 0.88 | MAPT (0.51) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL18153312 | 0.86 | LMNA (0.49) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL18153311 | 0.86 | MAPT (0.58) | LMNAMAPTGBA1BPTF | |
| SCHEMBL18063521 | 0.84 | MAPT (0.58) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL24784367 | 0.83 | LMNA (0.54) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL18063516 | 0.80 | LMNA (0.72) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL21744951 | 0.79 | RET (0.60) | — | |
| SCHEMBL18087188 | 0.79 | LMNA (0.63) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL18087196 | 0.78 | LMNA (0.60) | LMNAMAPTCCNE1CDK2ALDH1A1 | |
| SCHEMBL21015067 | 0.78 | LMNA (0.66) | LMNAMAPTCCNE1CDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |