Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | STK4 | Q13043 | 1/20 | 0.43 |
| ▸ | STK3 | Q13188 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123740 | 0.76 | ADRB1 (0.54) | PIK3CAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1123704 | 0.76 | ADRB1 (0.54) | PIK3CAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27581796 | 0.74 | USP2 (0.46) | ALDH1A1L3MBTL1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL6665691 | 0.73 | DHFR (0.51) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL5764480 | 0.73 | LMNA (0.46) | PIK3CAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30805488 | 0.71 | PIK3CA (0.83) | PIK3CAPIK3R1MTORPOLBPIK3CG | |
| SCHEMBL11862881 | 0.71 | ALDH1A1 (0.48) | PIK3CAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL778162 | 0.70 | HRH1 (0.65) | PIK3CAALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL778143 | 0.70 | HRH1 (0.65) | PIK3CAALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL10659846 | 0.70 | KDM4E (0.49) | PIK3CAALDH1A1KMT2AKDM4EPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |