Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679208 | 0.82 | SYK (0.47) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL560931 | 0.82 | ALDH1A1 (0.47) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL560930 | 0.82 | ALDH1A1 (0.47) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL2024317 | 0.81 | CA12 (0.48) | SYKALDH1A1MAPK1CTSSCA12 | |
| SCHEMBL8278320 | 0.81 | CA12 (0.48) | SYKALDH1A1MAPK1CTSSCA12 | |
| SCHEMBL16798515 | 0.80 | MAPT (0.52) | SYKL3MBTL1CTSSKLK7KLK5 | |
| SCHEMBL1152778 | 0.80 | CTSS (0.49) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL1152783 | 0.80 | CTSS (0.49) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL1153755 | 0.80 | CTSS (0.49) | SYKALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL560838 | 0.79 | ALDH1A1 (0.51) | SYKALDH1A1MAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |