Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154447 | 0.82 | SYK (0.47) | SYKPPARAKLK7KLK5ALDH1A1 | |
| SCHEMBL560683 | 0.80 | ALDH1A1 (0.49) | SYKPPARAKLK7KLK5ALDH1A1 | |
| SCHEMBL560684 | 0.80 | ALDH1A1 (0.49) | SYKPPARAKLK7KLK5ALDH1A1 | |
| SCHEMBL5318899 | 0.79 | CYP2D6 (0.36) | MEN1KMT2ACTSSCA12CA1 | |
| SCHEMBL999885 | 0.79 | KMT2A (0.45) | KMT2A | |
| SCHEMBL999886 | 0.79 | KMT2A (0.45) | KMT2A | |
| SCHEMBL560838 | 0.79 | ALDH1A1 (0.51) | SYKPPARAKLK7KLK5ALDH1A1 | |
| SCHEMBL643209 | 0.78 | SYK (0.46) | SYKPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL27341323 | 0.78 | ALDH1A1 (0.46) | SYKPPARAKLK7KLK5ALDH1A1 | |
| SCHEMBL27847368 | 0.78 | ALDH1A1 (0.46) | SYKPPARAKLK7KLK5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479579-B2 | Therapeutic compounds and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-10-25 | — | — | US | disclosed |
| US-20210277055-A1 | THERAPEUTIC COMPOUNDS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-09-09 | — | — | US | disclosed |
| US-6344452-B1 | GASTRIN RECEPTOR ANTAGONIST, GASTROINTESTINAL DISORDERS, ETC | ZERIA PHARMACEUTICALS CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1085014-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | Zeria Pharmaceutical Co., Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479579-B2 | Therapeutic compounds and methods | SNCA, PARK7, PSEN2 | SYK 3900/4885PPARA 2032/4885KLK7 4287/4885 |
| US-20210277055-A1 | THERAPEUTIC COMPOUNDS AND METHODS | SNCA, PARK7, PSEN2 | SYK 3900/4885PPARA 2032/4885KLK7 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.