Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.70 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816127 | 0.88 | MEN1 (0.84) | RAB9AKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL677770 | 0.88 | RAB9A (1.00) | RAB9AMEN1KMT2ANPC1KCNK3 | |
| SCHEMBL6242208 | 0.86 | RAB9A (0.84) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28268751 | 0.86 | RAB9A (0.74) | RAB9AMEN1KMT2ANPC1KCNK3 | |
| SCHEMBL1815384 | 0.85 | RAB9A (0.80) | RAB9AMEN1KMT2ANPC1KCNK3 | |
| SCHEMBL4926196 | 0.85 | RAB9A (0.74) | RAB9AMEN1KMT2ANPC1ATM | |
| SCHEMBL11710023 | 0.84 | RAB9A (0.76) | RAB9AKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL2358354 | 0.84 | MEN1 (1.00) | RAB9AMEN1KMT2ANPC1KCNK3 | |
| SCHEMBL677703 | 0.84 | RAB9A (0.86) | RAB9AKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL25138816 | 0.84 | RAB9A (0.91) | RAB9AKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046765-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-2318358-A2 | ACYLAMINOBENZAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2046765-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012027-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | RAB9A 742/4885KDM4E 849/4885MEN1 3469/4885 |
| US-20100048652-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | RAB9A 330/4885KDM4E 1978/4885MEN1 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.