Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502263 | 0.78 | MAPT (0.55) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL833283 | 0.78 | MAPT (0.55) | MAPTTDP1KDM4ENPC1POLB | |
| Hydrochloric Acid SCHEMBL629175 | 0.76 | MAPT (0.53) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL9717151 | 0.76 | MAPT (0.48) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL27544704 | 0.74 | NPC1 (0.55) | MAPTKDM4ENPC1RAB9AIDO1 | |
| SCHEMBL1143502 | 0.73 | RAPGEF4 (0.55) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL15977265 | 0.73 | CA12 (0.35) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL3509133 | 0.73 | ABCG2 (0.39) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL670295 | 0.73 | MEN1 (0.57) | MAPTTDP1KDM4ENPC1POLB | |
| SCHEMBL11942144 | 0.73 | CA2 (0.52) | MAPTTDP1KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531029-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2016-10-19 | — | — | EP | disclosed |