SCHEMBL833283

SCHEMBL833283

NNc1ccc(Cl)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
NPC1 O15118 3/20 0.55
KDM4E B2RXH2 2/20 0.55
RAB9A P51151 2/20 0.55
POLB P06746 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
IDO1 P14902 1/20 0.55
GAA P10253 2/20 0.53
EPHX1 P07099 2/20 0.52
EPHX2 P34913 2/20 0.52
GLA P06280 1/20 0.50
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47
CYP3A4 P08684 2/20 0.46
TSHR P16473 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502263 1.00 MAPT (0.55) MAPTNPC1KDM4ERAB9APOLB
Hydrochloric Acid SCHEMBL629175 0.97 MAPT (0.53) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL9717151 0.82 MAPT (0.48) MAPTNPC1KDM4ERAB9APOLB
Tert-Butyl Formate SCHEMBL27996975 0.78 NPC1 (0.42) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL11942144 0.78 CA2 (0.52) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL18155423 0.78 MAPT (0.46) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL1143502 0.78 RAPGEF4 (0.55) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL670295 0.78 MEN1 (0.57) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL9823483 0.78 MAPT (0.52) MAPTNPC1KDM4ERAB9APOLB
SCHEMBL3539117 0.78 MAPT (0.50) MAPTNPC1KDM4ERAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110117256-B Synthesis method of bixafen 芮城县斯普伦迪生物工程有限公司 2023-06-30 CN claimed
CN-110117256-A A kind of synthetic method of biphenyl pyrrole bacterium amine 苪城县斯普伦迪生物工程有限公司 2019-08-13 CN claimed
CN-1807223-A Dynamic molecule base electron device based on hydrazine derived biological molecular material UNIV FUDAN (CN) 2006-07-26 CN claimed
EP-0918052-B1 Improved polymeric mdi color BAYER AG (US) 2003-05-28 EP claimed
US-RE50878-E1 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-05 US disclosed
WO-2025122865-A1 BIFUNCTIONAL ABL1-BINDING COMPOUNDS AND USES THEREOF PHOTYS THERAPEUTICS, INC. (US) 2025-06-12 WO disclosed
CN-117486801-A Synthesis process for continuously preparing Ai Qubo Pa by using 3D printing forming technology 南京恒通医药开发有限公司 2024-02-02 CN disclosed
CN-110117256-B Synthesis method of bixafen 芮城县斯普伦迪生物工程有限公司 2023-06-30 CN disclosed
WO-2023284761-A1 PYRAZOLE ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 南通泰禾化工股份有限公司 2023-01-19 WO disclosed
WO-2023284833-A1 SPIROCYCLIC PIPERIDINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF 宜昌人福药业有限责任公司 2023-01-19 WO disclosed
WO-2022040157-A1 BORON CONTAINING COMPOUNDS AND THEIR USES 5METIS, INC. (US) 2022-02-24 WO disclosed
WO-2022040157-A1 BORON CONTAINING COMPOUNDS AND THEIR USES 5METIS, INC. (US) 2022-02-24 WO disclosed
US-4146721-A ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1979-03-27 US disclosed
US-4093812-A MICROBIOCIDES, DISINFECTANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1978-06-06 US disclosed
US-4060626-A Indole-carboxylic carbon compounds and pharmaceutical compositions containing them BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-11-29 US disclosed
US-4050918-A Herbicidal semicarbazides SHELL OIL COMPANY (US) 1977-09-27 US disclosed
US-4045169-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-4009181-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-02-22 US disclosed
US-3984463-A Herbicidal 2-phenyl semicarbazides SHELL OIL COMPANY (US) 1976-10-05 US disclosed
US-3957815-A 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed