Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928306 | 0.83 | BLM (0.59) | ALDH1A1TP53HPGDLMNAVNN1 | |
| SCHEMBL1947919 | 0.80 | MGLL (0.52) | MGLLALDH1A1TP53MAPK1HSD17B10 | |
| SCHEMBL12547325 | 0.78 | SMN1; SMN2 (0.63) | MGLLALDH1A1TP53MAPK1HPGD | |
| SCHEMBL1947109 | 0.78 | HPGD (0.65) | MGLLALDH1A1TP53MAPK1HPGD | |
| SCHEMBL14663384 | 0.77 | HPGD (0.59) | MGLLALDH1A1TP53MAPK1HPGD | |
| SCHEMBL7906862 | 0.76 | HPGD (0.66) | MGLLALDH1A1TP53MAPK1HPGD | |
| SCHEMBL5047494 | 0.74 | ACHE (0.67) | MGLLALDH1A1TP53HSD17B10HPGD | |
| SCHEMBL2476582 | 0.74 | L3MBTL1 (0.62) | MGLLALDH1A1HPGDTSHR | |
| SCHEMBL14107680 | 0.74 | SIGMAR1 (0.65) | MGLLALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL5047484 | 0.71 | MGLL (0.62) | MGLLALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081553-A1 | SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2016-10-19 | — | — | EP | disclosed |