Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055847 | 0.86 | TSHR (0.38) | TSHRGRIK1GRIK2 | |
| SCHEMBL28886205 | 0.83 | LMNA (0.58) | TSHRLMNAL3MBTL1 | |
| SCHEMBL1274363 | 0.83 | LMNA (0.58) | TSHRLMNAL3MBTL1 | |
| SCHEMBL20211165 | 0.83 | LMNA (0.58) | TSHRLMNAL3MBTL1 | |
| SCHEMBL5550234 | 0.83 | LMNA (0.58) | TSHRLMNAL3MBTL1 | |
| SCHEMBL5549387 | 0.83 | LMNA (0.58) | TSHRLMNAL3MBTL1 | |
| SCHEMBL1275043 | 0.81 | TDP1 (0.60) | TSHRLMNAL3MBTL1 | |
| SCHEMBL1589961 | 0.81 | TDP1 (0.60) | TSHRLMNAL3MBTL1 | |
| SCHEMBL3682095 | 0.81 | TDP1 (0.60) | TSHRLMNAL3MBTL1 | |
| SCHEMBL20211163 | 0.81 | TDP1 (0.60) | TSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008183-A | SOAPS USED ON THE SKIN COMPRISING A GLYCEROL DERIVATIVE, AT LEAST ONE SILICONE AND SURFACTANT, PROVIDING COMFORT AND SMOOTH TOUCH ON THE SKIN AFTER CLEANSING | KAO CORPORATION (JP) | 1999-12-28 | — | — | US | claimed |
| US-5856284-A | Detergent composition including a glycerol derivative, a polyhydric alcohol, and an amphoteric surfactant | KAO CORPORATION (JP) | 1999-01-05 | — | — | US | claimed |
| US-5681804-A | SKIN CLEANSER; MOISTURIZING WITHOUT STICKINESS OR TACKINESS AND WITHOUT EXCESS DEGREASING OR DRYNESS | KAO CORPORATION (JP) | 1997-10-28 | — | — | US | claimed |
| EP-0531684-B1 | Detergent composition | KAO CORP (JP) | 1997-10-08 | — | — | EP | claimed |
| US-5496492-A | MIXTURE OF GLYCEROL DERIVATIVE, POLYHYDRIC ALCOHOL, AND NONIONIC SURFACTANT; SKIN CLEANER; NONSTICKY FEEL | KAO CORPORATION (JP) | 1996-03-05 | — | — | US | claimed |
| EP-0531684-A1 | Detergent composition | KAO CORPORATION (JP) | 1993-03-17 | — | — | EP | claimed |
| CN-107613767-B | Synergistic preservative composition | ISP投资有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-107613767-A | Cooperate with anticorrosive composite | ISP投资有限公司 | 2018-01-19 | — | — | CN | disclosed |
| EP-2708526-B1 | Surfactant compositions and use for aqueous compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9388106-B2 | Surfactant compositions and use for aqueous compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140080745-A1 | SURFACTANT COMPOSITIONS AND USE FOR AQUEOUS COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC | 2014-03-20 | — | — | US | disclosed |
| EP-2708526-A1 | Surfactant compositions and use for aqueous compositions | Dow Global Technologies LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20130244984-A1 | Ceramide Production Promoter | KAO CORPORATION (JP) | 2013-09-19 | — | — | US | disclosed |
| US-6008183-A | SOAPS USED ON THE SKIN COMPRISING A GLYCEROL DERIVATIVE, AT LEAST ONE SILICONE AND SURFACTANT, PROVIDING COMFORT AND SMOOTH TOUCH ON THE SKIN AFTER CLEANSING | KAO CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| WO-1995028146-A1 | FLUOROCHEMICAL EMULSIONS CONTAINING 1,3-DIALKYLGLYCEROPHOSPHORYL CHOLINE SURFACTANTS AND METHODS OF USE | HEMAGEN/PFC (US) | 1995-10-26 | — | — | WO | disclosed |
| EP-0526537-B1 | 5-BENZYL BARBITURATE DERIVATIVES | UNIV BROWN RES FOUND (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0526537-A1 | 5-BENZYL BARBITURATE DERIVATIVES. | UNIV BROWN RES FOUND (US) | 1993-02-10 | — | — | EP | disclosed |
| US-5141943-A | Water soluble uridine phosphorylase inhibitors, reducing toxicity and anemia of antiviral drugs | BROWN UNIVERSITY RESEARCH FOUNDATION (US) | 1992-08-25 | — | — | US | disclosed |
| WO-1991016880-A1 | LIPOSOMES WITH POSITIVE EXCESS CHARGE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1991-11-14 | — | — | WO | disclosed |
| WO-1991016315-A1 | 5-BENZYL BARBITURATE DERIVATIVES | BROWN UNIVERSITY RESEARCH FOUNDATION (US) | 1991-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244984-A1 | Ceramide Production Promoter | CERS2, SPTLC1, SGMS1 | TSHR 3567/4885GRIK1 3742/4885GRIK2 4232/4885 |
| US-20140080745-A1 | SURFACTANT COMPOSITIONS AND USE FOR AQUEOUS COMPOSITIONS | SGMS2, SCP2, SGMS1 | TSHR 3121/4885GRIK1 3764/4885GRIK2 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.