Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379551 | 0.84 | AKR1C3 (0.48) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL18155869 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAGAAMEN1 | |
| SCHEMBL7183105 | 0.81 | CES2 (0.33) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL109891 | 0.76 | ALDH1A1 (0.50) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL27437106 | 0.76 | L3MBTL1 (0.41) | AKR1C3ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL1666971 | 0.76 | ALDH1A1 (0.50) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL30007458 | 0.76 | ALDH1A1 (0.50) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL10007412 | 0.75 | ALDH1A1 (0.59) | AKR1C3NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL4583573 | 0.74 | MEN1 (0.36) | AKR1C3ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL7183622 | 0.74 | L3MBTL1 (0.40) | AKR1C3ALDH1A1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877500-B1 | PHOTOPOLYMERISATION PROCESSES AND NOVEL COMPOUNDS THEREFOR | LAMBSON LTD (GB) | 2016-10-19 | — | — | EP | disclosed |