SCHEMBL18155869

SCHEMBL18155869

Cc1cc(C)c(C(=O)c2ccccc2)c(C)c1C(=O)Pc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
MAPT P10636 4/20 0.40
LMNA P02545 3/20 0.40
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
BCL2L1 Q07817 1/20 0.38
HTT P42858 1/20 0.38
GRM6 O15303 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
HPGD P15428 3/20 0.36
PLA2G1B P04054 1/20 0.36
MAPK1 P28482 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
SRD5A2 P31213 1/20 0.35
RAB9A P51151 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175269 0.84 HSD17B10 (0.33) ALDH1A1MAPTLMNACES2CES1
Lithium SCHEMBL7185553 0.84 HSD17B10 (0.33) ALDH1A1MAPTLMNACES2CES1
SCHEMBL18155855 0.82 AKR1C3 (0.39) ALDH1A1MAPTLMNAHPGDMAPK1
SCHEMBL7186976 0.80 ALDH1A1 (0.35) ALDH1A1MAPTLMNATDP1L3MBTL1
SCHEMBL15552435 0.80 AKR1C3 (0.48) ALDH1A1MAPTLMNAATMTDP1
SCHEMBL29378123 0.80 AKR1C3 (0.48) ALDH1A1MAPTLMNAATMTDP1
SCHEMBL28303936 0.79 CRHR1 (0.33) MAPTLMNAATMTDP1RAB9A
SCHEMBL98044 0.78 LMNA (0.38) ALDH1A1LMNAL3MBTL1HPGDMEN1
SCHEMBL18155901 0.78 LMNA (0.47) ALDH1A1MAPTLMNAATMTDP1
SCHEMBL7183105 0.77 CES2 (0.33) ALDH1A1MAPTLMNATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2877500-B1 PHOTOPOLYMERISATION PROCESSES AND NOVEL COMPOUNDS THEREFOR LAMBSON LTD (GB) 2016-10-19 EP disclosed