Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628018 | 0.91 | HPGD (0.39) | MAPTHPGDALDH1A1SMN1; SMN2SRC | |
| SCHEMBL22056822 | 0.84 | PTGS2 (0.41) | MAPTHPGDALDH1A1SMN1; SMN2SRC | |
| SCHEMBL16273653 | 0.77 | MAPT (0.39) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16627217 | 0.77 | MAPT (0.39) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16911183 | 0.76 | MAPT (0.37) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16273747 | 0.76 | SMN1; SMN2 (0.38) | MAPTHPGDALDH1A1SMN1; SMN2SRC | |
| SCHEMBL16273682 | 0.76 | HPGD (0.38) | MAPTHPGDALDH1A1SMN1; SMN2SRC | |
| SCHEMBL16628020 | 0.74 | GRM2 (0.39) | MAPTHPGDALDH1A1SMN1; SMN2SRC | |
| SCHEMBL16910940 | 0.74 | SENP2 (0.38) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16627158 | 0.70 | ACLY (0.43) | MAPTHPGDSMN1; SMN2SRCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081559-A1 | AROMATIC COMPOUND AND APPLICATION FOR SAME | Sumitomo Chemical Company, Limited (JP) | 2016-10-19 | — | — | EP | disclosed |