SCHEMBL16627158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15330426	0.90	TDP2 (0.43)	ACLYMAPTKMT2ATDP2KDM4E
	SCHEMBL16627900	0.86	ALDH1A1 (0.40)	ACLYMAPTKMT2ACYP1A2CYP2C9
	SCHEMBL16627217	0.86	MAPT (0.39)	ACLYMAPTKMT2ACYP1A2CYP2C9
	SCHEMBL2558362	0.86	ERN1 (0.44)	ACLYPTGS2KMT2APTGS1KDM4E
	SCHEMBL22056822	0.85	PTGS2 (0.41)	PTGS2SRCABL1MAPTKMT2A
	SCHEMBL16627212	0.82	ACLY (0.42)	ACLYPTGS2SRCABL1MAPT
	SCHEMBL16273643	0.82	ESR2 (0.40)	ACLYSRCABL1KMT2ACYP1A2
	SCHEMBL15330077	0.80	KMT2A (0.45)	MAPTKMT2ACYP1A2CYP2C9CYP2C19
	SCHEMBL15330444	0.78	RIPK2 (0.39)	SRCABL1KMT2ACYP1A2CYP2C9
	SCHEMBL15331791	0.78	CYP1A2 (0.46)	MAPTKMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.