SCHEMBL18156885

SCHEMBL18156885

Cc1ccc2ccc(O)c(C=O)c2c1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 16/20 0.59
ALB P02768 1/20 0.47
TRPA1 O75762 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22750626 0.87 ERN1 (0.65) ERN1
SCHEMBL3906221 0.81 ERN1 (0.63) ERN1
SCHEMBL3268690 0.81 CYP2A6 (0.48) ERN1ALB
SCHEMBL31276106 0.81 ERN1 (0.63) ERN1
SCHEMBL21122870 0.79 CYP2A6 (0.42) ERN1ALB
SCHEMBL28800881 0.79 ERN1 (0.61) ERN1
SCHEMBL18717305 0.78 ERN1 (0.70) ERN1
SCHEMBL19305533 0.78 ERN1 (0.77) ERN1
SCHEMBL5229299 0.77 ERN1 (0.57) ERN1
SCHEMBL14440490 0.77 ERN1 (0.54) ERN1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
US-20170313715-A1 SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2017-11-02 US disclosed
US-9701608-B2 Process for the synthesis of 7-methoxy-naphthalene-1-carbaldehyde and application in the synthesis of agomelatine LES LABORATORIES SERVIER (FR) 2017-07-11 US disclosed
US-20160304429-A1 PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE LES LABORATOIRES SERVIER (FR) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304429-A1 PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE COMT, TPH1, TPH2 ERN1 2609/4885ALB 3036/4885TRPA1 3936/4885
US-20170313715-A1 SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF DPP4, DPP7, DPP3 ERN1 3887/4885ALB 3255/4885TRPA1 2457/4885
US-20230131561-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT AND IMAGE DISPLAY DEVICE SF1, SPIN1, RER1 ERN1 1172/4885ALB 3621/4885TRPA1 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.